BDBM50517145 CHEMBL4578235

SMILES CCCCN(Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1nc2cc(ccc2o1)C(=O)OC

InChI Key InChIKey=SIRUESMRMAUACO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50517145   

TargetChemerin-like receptor 1(Human)
Kyowa Kirin

Curated by ChEMBL
LigandPNGBDBM50517145(CHEMBL4578235)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of chemR23 in human CAL1 cells assessed as reduction in chemerin-induced intracellular calcium ion concentration preincubated for 45 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Kyowa Kirin

Curated by ChEMBL
LigandPNGBDBM50517145(CHEMBL4578235)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CXCR4 expressed in human CAL1 cells assessed as reduction in SDF1alpha-induced intracellular calcium ion concentration preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetChemerin-like receptor 1(Human)
Kyowa Kirin

Curated by ChEMBL
LigandPNGBDBM50517145(CHEMBL4578235)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed