BDBM50517021 CHEMBL4445985

SMILES CC(C)CCOc1ccc(cc1C#N)-c1ncc(C(O)=O)c(=N)[nH]1

InChI Key InChIKey=ZEEAXDGUEMBVMX-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50517021   

TargetXanthine dehydrogenase/oxidase(Bovine)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50517021(CHEMBL4445985)
Affinity DataIC50: 24nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated with enzyme for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50517021(CHEMBL4445985)
Affinity DataIC50: 29nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 15 mins followed by substrate addition by UV spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50517021(CHEMBL4445985)
Affinity DataKi:  4.20nMAssay Description:Mixed type inhibition of bovine xanthine oxidase using xanthine as substrate preincubated with enzyme for 15 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50517021(CHEMBL4445985)
Affinity DataKi:  4.20nMAssay Description:Mixed-type inhibition of xanthine oxidase (unknown origin) assessed as inhibitory constant of enzyme-substrate complex using xanthine as substrate at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50517021(CHEMBL4445985)
Affinity DataKi:  127nMAssay Description:Mixed type inhibition of bovine xanthine oxidase using xanthine as substrate preincubated with enzyme for 15 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed