BDBM50516998 CHEMBL4552542

SMILES COc1cccc(CN2CCC(=CC2)c2c[nH]c3ccccc23)c1

InChI Key InChIKey=ALKXNIXXISSQFE-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50516998   

Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516998(CHEMBL4552542)
Affinity DataIC50: 7.98E+3nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516998(CHEMBL4552542)
Affinity DataIC50: 7.94E+3nMAssay Description:Antagonist activity at human 5HT2A receptor expressed in CHOK1 cells assessed as inhibition of 5-HT induced inositol phosphate production incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516998(CHEMBL4552542)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]Spiperone from human D2S receptor expressed in CHOK1 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516998(CHEMBL4552542)
Affinity DataKi:  194nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50516998(CHEMBL4552542)
Affinity DataKi:  243nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed