BDBM50516911 CHEMBL4461587

SMILES CC#CCn1c(nc2n(C)c(=O)n(Cc3ccc(Br)cc3C(O)=O)c(=O)c12)N1CCC[C@@H](N)C1

InChI Key InChIKey=MTVFAHPEFYZIQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516911   

TargetDipeptidyl peptidase 8(Human)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50516911(CHEMBL4461587)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition measured at 60 secs interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50516911(CHEMBL4461587)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of recombinant human DPP4 expressed in baculovirus infected Sf9 insect cells using Gly-Pro-AMC as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50516911(CHEMBL4461587)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP9 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition measured at 60 secs interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed