BDBM50515702 CHEMBL4467593

SMILES Cc1ccc2oc(=O)c3cc(C4=Nc5ccc(cc5N=CC4)C(=O)c4ccccc4)c(=O)oc3c2c1

InChI Key InChIKey=NGHPUTDWYDAKHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50515702   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50515702(CHEMBL4467593)
Affinity DataIC50: 4.29E+4nMAssay Description:Inhibition of His6-tagged HIV-1 reverse transcriptase RNase H using 5'-GTTTTCTTTTCCCCCCTGAC-3'-Fluorescein-labeled RNA/5'-CAAAAGAAAAGGGGGGACUG-3'-Dab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50515702(CHEMBL4467593)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LEDGF/p75-dependent full length HIV-1 integrase expressed in Escherichia coli BL21(DE3) cells preincubated for 1 hr further incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed