BDBM50515701 CHEMBL4465730

SMILES Oc1c(C2=Nc3ccc(cc3N=CC2)C(=O)c2ccccc2)c(=O)oc2c3ccccc3oc(=O)c12

InChI Key InChIKey=XIEGXRIVEOCFHD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50515701   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50515701(CHEMBL4465730)
Affinity DataIC50: 3.84E+4nMAssay Description:Inhibition of His6-tagged HIV-1 reverse transcriptase RNase H using 5'-GTTTTCTTTTCCCCCCTGAC-3'-Fluorescein-labeled RNA/5'-CAAAAGAAAAGGGGGGACUG-3'-Dab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50515701(CHEMBL4465730)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of subunit exchanging activity of His and Flag-tagged HIV-1 integrase expressed in Escherichia coli BL21(DE3) cells after 2.5 hrs by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50515701(CHEMBL4465730)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of LEDGF/p75-dependent full length HIV-1 integrase expressed in Escherichia coli BL21(DE3) cells preincubated for 1 hr further incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed