BDBM50515572 CHEMBL4533885
SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)N2CCN(CC2)C(=O)Nc2ccc(cc2)C(C)=O)cc1
InChI Key InChIKey=ZTLKLIIMWKVDRO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50515572
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal His-tagged human JAK2 catalytic domain (826 to 1132 resiudes) expressed in baculovirus expression system using FAM-labeled p...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST-tagged human FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus expression system musing FAM-labeled...More data for this Ligand-Target Pair