BDBM50515519 CHEMBL4475456

SMILES NS(=O)(=O)c1ccc(CCN2C(=O)c3ccc(cc3C2=O)C(=O)Nc2ccc(Cl)cc2C(O)=O)cc1

InChI Key InChIKey=VDMQIQLKGNCVFC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50515519   

TargetCarbonic anhydrase 12(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50515519(CHEMBL4475456)
Affinity DataKi:  4.60nMAssay Description:Inhibition of recombinant human CA12 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50515519(CHEMBL4475456)
Affinity DataKi:  7.30nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50515519(CHEMBL4475456)
Affinity DataKi:  16nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50515519(CHEMBL4475456)
Affinity DataKi:  231nMAssay Description:Inhibition of recombinant human CA1 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed