BDBM50515510 CHEMBL4547526

SMILES COc1ccc(NC(=O)c2ccc3C(=O)N(Cc4ccc(cc4)S(N)(=O)=O)C(=O)c3c2)c(c1)C(O)=O

InChI Key InChIKey=XCFBYGHTZLADMA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50515510   

TargetCarbonic anhydrase 9(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50515510(CHEMBL4547526)
Affinity DataKi:  36nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50515510(CHEMBL4547526)
Affinity DataKi:  52nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50515510(CHEMBL4547526)
Affinity DataKi:  75nMAssay Description:Inhibition of recombinant human CA12 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50515510(CHEMBL4547526)
Affinity DataKi:  457nMAssay Description:Inhibition of recombinant human CA1 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed