BDBM50515385 CHEMBL4472094

SMILES CCCCCn1cc(C(=O)N[C@@H](C(C)C)C(N)=O)c2cccnc12

InChI Key InChIKey=XCLPUCIBZGBWJW-UHFFFAOYSA-N

Data  4 KI  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50515385   

TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  121nMAssay Description:Agonist activity at human CB1 receptor expressed in AtT-20 cells measured every 2 secs for 2 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  59nMAssay Description:Agonist activity at human CB2 receptor expressed in AtT-20 cells measured every 2 secs for 2 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human CB2 receptor expressed in AtT-20 cells measured every 2 secs for 2 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human CB1 receptor expressed in AtT-20 cells measured every 2 secs for 2 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human CB1 receptor expressed in mouse AtT20 cells incubated for 60 mins by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  101nMAssay Description:Agonist activity at human CB1 receptor expressed in mouse AtT20 cells incubated for 60 mins by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human CB2 receptor expressed in mouse AtT20 cells incubated for 60 mins by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human CB2 receptor expressed in mouse AtT20 cells incubated for 60 mins by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  4.17E+3nMAssay Description:Agonist activity at CB1 receptor (unknown origin) expressed in human HEK293T cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  4.15E+3nMAssay Description:Agonist activity at CB1 receptor (unknown origin) expressed in human HEK293T cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  692nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in human HEK293T cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataEC50:  694nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in human HEK293T cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in human HEK293-EBNA cells incubated for 60 mins by radioligand competitive binding as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in human HEK293-EBNA cells incubated for 60 mins by radioligand competitive binding as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]-CP55940 from N-terminal 3HA-tagged human CB2 receptor expressed in human HEK293-EBNA cells incubated for 60 mins by radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50515385(CHEMBL4472094)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]-CP55940 from N-terminal 3HA-tagged human CB2 receptor expressed in human HEK293-EBNA cells incubated for 60 mins by radioligand ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed