BDBM50515093 CHEMBL4541650

SMILES CN1CCN(CC1)c1ccc(Nc2nc(sc2C(N)=O)-c2cccc(NC(=O)c3ccc(F)c(Cl)c3)c2)cc1

InChI Key InChIKey=YEKUKSJVXZCPIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50515093   

TargetTyrosine-protein kinase BTK(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50515093(CHEMBL4541650)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant full length N-terminal His tagged BTK expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50515093(CHEMBL4541650)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant full length N-terminal His tagged BTK C481S mutant expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed