BDBM50514778 CHEMBL4466702

SMILES [H][C@@]12CCC[C@]1([H])N([C@@H](C2)c1ncc([nH]1)-c1ccc2c(c1)n(C)c1cc(ccc21)-c1cnc([nH]1)[C@@H]1C[C@]2([H])CCC[C@]2([H])N1C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC)C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC

InChI Key InChIKey=KCIXCDPQMJNLAF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514778   

TargetNonstructural protein 5A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50514778(CHEMBL4466702)
Affinity DataEC50:  0.0280nMAssay Description:Inhibition of NS5A in HCV genotype 1b infected in HuH-Lcu-Neo cells assessed as reduction in viral replication incubated for 48 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50514778(CHEMBL4466702)
Affinity DataEC50:  0.148nMAssay Description:Inhibition of NS5A in HCV genotype 1a infected in HuH-Lcu-Neo cells assessed as reduction in viral replication incubated for 48 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed