BDBM50514487 CHEMBL1230705

SMILES CCCCCc1ccc(cc1)C(=O)N(Cc2ccc(cc2)N(C)c3ccncc3)C4CCN(CC4)CCC(C)C

InChI Key InChIKey=WRFRQUOWNCJODU-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514487   

TargetPlasmepsin II(Plasmodium falciparum)
University of Zambia

Curated by ChEMBL
LigandPNGBDBM50514487(CHEMBL1230705)
Affinity DataIC50: 113nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlasmepsin I(malaria parasite P. falciparum)
University of Zambia

Curated by ChEMBL
LigandPNGBDBM50514487(CHEMBL1230705)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPlasmepsin IV [1-448](malaria parasite P. falciparum)
University of Zambia

Curated by ChEMBL
LigandPNGBDBM50514487(CHEMBL1230705)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed