BDBM50514074 CHEMBL4539788

SMILES Cc1cc(ccc1-c1ccc(C[C@H](NC(=O)[C@H]2CC[C@H](CN)CC2)C(=O)Nc2ccc3c(c2)[nH][nH]c3=O)cc1)S(=O)(=O)N1CCCC1

InChI Key InChIKey=YKEUPPOASIWEHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514074   

TargetPlasminogen(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50514074(CHEMBL4539788)
Affinity DataIC50: 23nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor XI(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50514074(CHEMBL4539788)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human factor 11a preincubated for 15 mins followed by Boc-Glu (OBzl) -Ala-Arg-AMC and measured after 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed