BDBM50514013 CHEMBL4445673::US11247985, Table 3.55

SMILES CC(C)N1CCN(CCNC2CCN(CC2)c2cccc(c2)-c2cc3cc(ccc3[nH]2)C#N)CC1

InChI Key InChIKey=NIPXJLUDQRAINK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514013   

LigandPNGBDBM50514013(CHEMBL4445673 | US11247985, Table 3.55)
Affinity DataIC50: 44nMAssay Description:Inhibition of p97 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
LigandPNGBDBM50514013(CHEMBL4445673 | US11247985, Table 3.55)
Affinity DataIC50: 26nMAssay Description:To optimize p97 inhibitors, the C-5 trifluoromethylated trifluoromethylated indole 12 was generated as a promising lead structure. In the ADP-Glo ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
Go to US Patent