BDBM50513344 CHEMBL4447515

SMILES Fc1cccc(c1)C1CCN(CCc2cnn(c2)-c2nccc3c2nc[nH]c3=O)CC1

InChI Key InChIKey=FJLXFYHDLHZPQK-UHFFFAOYSA-N

Data  2 KI  7 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50513344   

TargetLysine-specific demethylase 5B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataIC50: 29nMAssay Description:Inhibition of KDM5B (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 5B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataEC50:  2.90E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM5B (26 to 772 residues) fused with ePL-tagged C-terminal transfected in HEK293T cells measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataIC50: 84nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 5C(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataIC50: 96nMAssay Description:Inhibition of KDM5C (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 2A(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of KDM2A (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 6B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KDM6B (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataEC50:  2.00E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3A(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataIC50: 6.42E+3nMAssay Description:Inhibition of KDM3A (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 5B(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataKi:  3nMAssay Description:Binding affinity to KDM5B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataKi:  4nMAssay Description:Binding affinity to KDM4A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed