BDBM50512537 CHEMBL4474736

SMILES Cn1nc(COc2cccc(F)c2)c2CN(CCc12)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=YOWSXWDXCBUJCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512537   

TargetPendrin(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50512537(CHEMBL4474736)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPendrin(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50512537(CHEMBL4474736)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed