BDBM50512459 CHEMBL4581793

SMILES O=C(Cc1ccccc1)Nc1ccc(cc1)-c1ccc2nc(Nc3ccccc3C#N)nn2c1

InChI Key InChIKey=RPGJGJRXGBZPLW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50512459   

TargetDual specificity protein kinase TTK(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50512459(CHEMBL4581793)
Affinity DataIC50: 1nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50512459(CHEMBL4581793)
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50512459(CHEMBL4581793)
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged recombinant human MPS1 expressed in baculovirus expression system using biotin-Ahx-PWDPDDADITEILG as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50512459(CHEMBL4581793)
Affinity DataIC50: 1nMAssay Description:Inhibition of human MPS1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed