BDBM50512085 CHEMBL4592912

SMILES ONC(=O)CCn1cc(Nc2ncc(Cl)c(Nc3ccc(F)cc3)n2)cn1

InChI Key InChIKey=GCVCURZWFLHLHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512085   

TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512085(CHEMBL4592912)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512085(CHEMBL4592912)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human JAK2 using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed