BDBM50511717 CHEMBL4437257

SMILES [H][C@@]1(c2ccccc2-c2cncn12)[C@]1([H])CCc2cnccc2[C@H]1O

InChI Key InChIKey=SXSSPSBEERTCTN-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511717   

TargetTryptophan 2,3-dioxygenase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50511717(CHEMBL4437257)
Affinity DataEC50:  48nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50511717(CHEMBL4437257)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50511717(CHEMBL4437257)
Affinity DataEC50:  800nMAssay Description:Inhibition of IDO1 in human A172 cells after 24 hrs in presence of IFNgamma by NFK green reagent based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed