BDBM50511345 CHEMBL4566548

SMILES OP(O)(=O)Oc1cccc(OP(O)(O)=O)c1OP(O)(O)=O

InChI Key InChIKey=ALWMWBDJLPREOH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50511345   

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511345(CHEMBL4566548)
Affinity DataIC50: 1.42E+4nMAssay Description:Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetType II inositol 1,4,5-trisphosphate 5-phosphatase(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511345(CHEMBL4566548)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged INPP5B (259 to 563 residues) expressed in Escherichia coli BL21 (DE3) incubated for 5 mins usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetInositol polyphosphate-5-phosphatase A(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511345(CHEMBL4566548)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511345(CHEMBL4566548)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of Ins(1,3,4,5)P4 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed