BDBM50511343 CHEMBL4473747

SMILES OP(O)(=O)Oc1ccc(OP(O)(O)=O)c(OP(O)(O)=O)c1

InChI Key InChIKey=XPWCRVGWWKLQCK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511343   

TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511343(CHEMBL4473747)
Affinity DataIC50: 7.02E+3nMAssay Description:Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetInositol polyphosphate-5-phosphatase A(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511343(CHEMBL4473747)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50511343(CHEMBL4473747)
Affinity DataIC50: 6.25E+3nMAssay Description:Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed