BDBM50511108 CHEMBL4558185

SMILES [H][C@]12N(CCC[C@@]1(CC)C=C(C(=O)OC)n1c2c(CCNC(=O)c2ccc(Br)cc2)c2ccccc12)C#N

InChI Key InChIKey=IUXSPRUXYTWDEG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50511108   

TargetC-C chemokine receptor type 8(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50511108(CHEMBL4558185)
Affinity DataIC50: 5.20E+3nMAssay Description:Antagonist activity at human CCR8 expressed in CHOK1 cells assessed as reduction in CCL1-induced beta-arrestin 2 recruitment incubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50511108(CHEMBL4558185)
Affinity DataIC50: 1.08E+3nMAssay Description:Antagonist activity at human Gi/o-coupled FPR1 expressed in CHOK1 cells assessed as reduction in WKYMVm-NH2-induced beta-arrestin 2 recruitment incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50511108(CHEMBL4558185)
Affinity DataIC50: 5.77E+3nMAssay Description:Antagonist activity at human Gq-coupled NPSR1b expressed in human U2OS cells assessed as inhibition in neuropeptide S-induced beta-arrestin 2 recruit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProlactin-releasing peptide receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50511108(CHEMBL4558185)
Affinity DataIC50: 2.43E+3nMAssay Description:Antagonist activity at human Gq-coupled PRLHR expressed in CHOK1 cells assessed as inhibition in prolactin releasing peptide (1 to 31)-induced beta-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed