BDBM50510906 CHEMBL4435880

SMILES CC(C(=O)NCc1cccnc1C1CCCN(C)CC1)n1cncc1C

InChI Key InChIKey=LCFCRUDLPGTLCB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50510906   

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50510906(CHEMBL4435880)
Affinity DataKi:  15nMAssay Description:Inhibition of human NMT1 R295Q/W297F/A452M/L453V/L462V/N473H/L495M/Q496L mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50510906(CHEMBL4435880)
Affinity DataKi:  52nMAssay Description:Inhibition of N-terminal TEV cleavage site-fused His6 tagged Leishmania major NMT (11 to 421 residues) expressed in Escherichia coli Rosetta-2 cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Johannes Gutenberg-Universit£T Mainz

Curated by ChEMBL
LigandPNGBDBM50510906(CHEMBL4435880)
Affinity DataKi: >200nMAssay Description:Inhibition of N-terminal TEV cleavage site-fused His6 tagged human NMT1 (115 to 496 residues) expressed in Escherichia coli Rosetta-2 cells using GSN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed