BDBM50510888 CHEMBL4544826

SMILES COc1cc2ncnc(-n3ncc4cc(NC(=O)Nc5ccc(C)c(Cl)c5)ccc34)c2cc1OC

InChI Key InChIKey=VUSKLLROUKCZTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510888   

TargetVascular endothelial growth factor receptor 2(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50510888(CHEMBL4544826)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant GST-tagged VEGFR2 (catalytic domain 805 to 1356 residues) expressed in Sf9 insect cells incubated for 45 mins by Kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50510888(CHEMBL4544826)
Affinity DataIC50: 12nMAssay Description:Inhibition of VEGFR-2 (unknown origin) using poly(Glu:Tyr)(4:1) and ATP as substrate by incubated for 1 hr by spectrophotometric based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed