BDBM50510540 CHEMBL4445265

SMILES Cc1cc(=O)n2nc(SCc3ccc(cc3)[N+]([O-])=O)nc2[nH]1

InChI Key InChIKey=SEKBRVIHGSJFOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50510540   

TargetEpidermal growth factor receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50510540(CHEMBL4445265)
Affinity DataIC50: 76nMAssay Description:Inhibition of human recombinant GST-tagged EGFR L858R/T790M mutant expressed in baculovirus expression system reduction in phosphorylation using tyro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50510540(CHEMBL4445265)
Affinity DataIC50: 107nMAssay Description:Inhibition of human recombinant GST-tagged EGFR L858R mutant expressed in baculovirus expression system reduction in phosphorylation using tyrosine 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50510540(CHEMBL4445265)
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant His-tagged cMET expressed in baculovirus expression system reduction in phosphorylation using tyrosine 6 peptide as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed