BDBM50510519 CHEMBL4463377
SMILES OCCNC1CCN(C1)c1ccc2c(C(=O)NCC3CCC(F)(F)CC3)c(Cl)ccc2n1
InChI Key InChIKey=NOBBKTYSVABXBL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50510519
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair