BDBM50510071 CHEMBL4541082

SMILES CN1[C@@H](CCC1=O)C(=O)NCc1cccc(c1I)C(F)(F)F

InChI Key InChIKey=KIVRPCQQDABUOC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510071   

TargetP2X purinoceptor 7(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50510071(CHEMBL4541082)
Affinity DataIC50: 5.30nMAssay Description:Displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50510071(CHEMBL4541082)
Affinity DataKi:  1.90nMAssay Description:Competitive displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed