BDBM50509992 CHEMBL4439563

SMILES OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1c[nH]c2ccc(Cl)cc12

InChI Key InChIKey=JTDQDYHYTWJLPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509992   

TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50509992(CHEMBL4439563)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50509992(CHEMBL4439563)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed