BDBM50509985 CHEMBL4588868

SMILES OC(=O)c1cccc(NC(=O)c2c[nH]c3ccc(Cl)cc23)c1

InChI Key InChIKey=VRKFMHBODMUPES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509985   

TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50509985(CHEMBL4588868)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50509985(CHEMBL4588868)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed