BDBM50509376 CHEMBL4590233

SMILES [H][C@]12O[C@]([H])(c3c1c(C)c(O)c(OC)c3O)[C@@]1([H])C(=O)[C@@]34C(=O)N[C@@H](CC(C)C)[C@]3([H])[C@H](C)C(C)=C[C@]4([H])\C=C(C)\CC[C@@H](O)C(=O)[C@]21[H]

InChI Key InChIKey=HMFDSIGNMYZFJO-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50509376   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50509376(CHEMBL4590233)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 5 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed