BDBM50508526 CHEMBL4542245

SMILES CN1CCC(C1)NC(=O)c1ccncc1Nc1cc(-c2cc(F)c3ccn(C)c3c2)c2nccnc2c1

InChI Key InChIKey=UTQCFIUGBIYRNU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50508526   

LigandPNGBDBM50508526(CHEMBL4542245)
Affinity DataIC50: 480nMAssay Description:Inhibition of PFKFB3 in human HCT116 cell lysates assessed as reduction in glycolytic-flux induced fructose-2,6-bisphosphate formation using fructose...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50508526(CHEMBL4542245)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50508526(CHEMBL4542245)
Affinity DataIC50: 480nMAssay Description:Inhibition of PFKFB3 in human HCT-116 cells assessed as reduction in Fructose-2,6-Bisphosphate productionMore data for this Ligand-Target Pair
In DepthDetails
PubMed