BDBM50508416 CHEMBL4518815

SMILES Cn1ccc(Cn2c3ccc(cc3c(=O)n(Cc3cnn(C)c3)c2=O)S(=O)(=O)NC2(C)CC2)n1

InChI Key InChIKey=YIIIUBIPEMDTEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508416   

TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508416(CHEMBL4518815)
Affinity DataIC50: 90nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50508416(CHEMBL4518815)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed