BDBM50507538 CHEMBL4452256

SMILES COc1ccc(cn1)-c1ccc(Cn2cc(nn2)-c2cccc(Cl)c2)cc1

InChI Key InChIKey=WYLBYVHRCHPXRQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507538   

TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50507538(CHEMBL4452256)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of VEGFR2 (unknown origin) after 1 hr by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50507538(CHEMBL4452256)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50507538(CHEMBL4452256)
Affinity DataIC50: 29nMAssay Description:Inhibition of EPHB4 (unknown origin) after 4 hrs by ADP-Glo reagent based luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed