BDBM50507504 CHEMBL4537970

SMILES Cc1c(\C=C\c2cc(CNC(C)(CO)C(O)=O)ccc2C(F)(F)F)cccc1-c1ccc2OCCOc2c1

InChI Key InChIKey=PTGUEPRQUFAZLN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50507504   

TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50507504(CHEMBL4537970)
Affinity DataIC50: 18nMAssay Description:Inhibition of PD1/PDL1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50507504(CHEMBL4537970)
Affinity DataIC50: 18nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50507504(CHEMBL4537970)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at PD1/PD-L1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50507504(CHEMBL4537970)
Affinity DataIC50: 18nMAssay Description:Inhibition of PDL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50507504(CHEMBL4537970)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at PD-1/PD-L1 interaction (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed