BDBM50507276 CHEMBL4519297

SMILES NOC(c1ccccc1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=XURNFVZOPOLXKF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50507276   

TargetTryptophan 2,3-dioxygenase(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50507276(CHEMBL4519297)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of human TDO expressed in human T-REx cells using L-tryptophan as substrate after 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50507276(CHEMBL4519297)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of mouse IDO2 expressed in human T-REx cells using L-tryptophan as substrate after 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50507276(CHEMBL4519297)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of IDO1 in human HeLa cells using L-tryptophan as substrate after 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50507276(CHEMBL4519297)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of TDO (unknown origin) using L-tryptophan as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed