BDBM50506786 CHEMBL4469152

SMILES COc1ccc2c(NC3CCN(Cc4ccccc4)CC3)nc(nc2c1)N1CCN(CC1)c1ccccc1

InChI Key InChIKey=NWMXOHAWLAMXOO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506786   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506786(CHEMBL4469152)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506786(CHEMBL4469152)
Affinity DataEC50:  4.60E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed