BDBM50506750 CHEMBL2349625

SMILES CCc1c(C)sc(NC(=O)C23CC4CC(CC(C4)C2)C3)c1C(=O)OC

InChI Key InChIKey=NRZDWDWUMMFBOW-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50506750   

TargetCannabinoid receptor 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50506750(CHEMBL2349625)
Affinity DataEC50:  197nMAssay Description:Agonist activity at recombinant human CB2R expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levels after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50506750(CHEMBL2349625)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in HEK293 cell membranes measured after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50506750(CHEMBL2349625)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes measured after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed