BDBM50506717 CHEMBL3759098

SMILES O\N=C1/c2ccccc2-c2nc3ccccc3nc12

InChI Key InChIKey=SZHHSFHOIDCNLD-UHFFFAOYSA-N

Data  2 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50506717   

TargetMitogen-activated protein kinase 10/8/9(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50506717(CHEMBL3759098)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of JNK in human MONO-MAC-6 cells assessed as reduction in LPS-induced IL6 production preincubated for 30 mins followed by LPS-stimulation ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50506717(CHEMBL3759098)
Affinity DataKd:  360nMAssay Description:Binding affinity to human full-length JNK2 (M1 to Q382 residues) expressed in HEK293 cells measured after 1 hr by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50506717(CHEMBL3759098)
Affinity DataKd:  100nMAssay Description:Binding affinity to human partial length JNK3 (V28 to Q422 residues) expressed in HEK293 cells measured after 1 hr by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10/8/9(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50506717(CHEMBL3759098)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of JNK in human THP1-Blue cells assessed as reduction in LPS-induced NFkappaB/AP1 activation preincubated for 30 mins followed by LPS-stim...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM50506717(CHEMBL3759098)
Affinity DataKd:  240nMAssay Description:Binding affinity to human full-length JNK1 (M1 to Q384 residues) expressed in HEK293 cells measured after 1 hr by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed