BDBM50506273 CHEMBL4534434

SMILES CCCn1c(NC(=O)c2cc(C)nn2CC)nc2cc(ccc12)C(N)=O

InChI Key InChIKey=PIFQMGNPBKIDAY-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50506273   

TargetInterferon regulatory factor 3(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506273(CHEMBL4534434)
Affinity DataEC50: >1.00E+5nMAssay Description:Induction of IRF3 pathway in STING knockout human THP1 cells measured after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506273(CHEMBL4534434)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at STING in human THP1 cells assessed as stimulation of IRF3 pathway measured after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50506273(CHEMBL4534434)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of anti 6His antibody-labeled terbium cryptate binding to human wild-type full-length 6His-tagged d2-labeled STING measured after 4 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed