BDBM50506114 CHEMBL4461965

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]51C[C@H](c4ccccc4)[C@]2(OC)C=C1)ccc3OC

InChI Key InChIKey=QMPVAJYKJRMMQD-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506114   

TargetKappa-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50506114(CHEMBL4461965)
Affinity DataEC50:  175nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by liquid scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50506114(CHEMBL4461965)
Affinity DataKi:  7.89E+3nMAssay Description:Displacement of [3H]U69593 from human KOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed