BDBM50505986 CHEMBL4450661

SMILES CCc1nc([nH]c1-c1ccc-2c(OCC(C)(C)COc3cc(ccc-23)-c2[nH]c(nc2CC)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)OC)C(C)C)c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C

InChI Key InChIKey=RQBLNFWQRHEUJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505986   

TargetNonstructural protein 5A(Hepacivirus C)
Lupin

Curated by ChEMBL
LigandPNGBDBM50505986(CHEMBL4450661)
Affinity DataIC50: 0.219nMAssay Description:Inhibition of NS5A in HCV genotype 1b infected in human HuH7.5/Con1/SG-Neo(I)-hRluc2aUb cells assessed as inhibition of replicon levels incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Lupin

Curated by ChEMBL
LigandPNGBDBM50505986(CHEMBL4450661)
Affinity DataIC50: 80nMAssay Description:Inhibition of NS5A in HCV genotype 2a infected in human Huh7.5/J6/JFH1/EMCVIRES/hRlucNeo cells assessed as inhibition of replicon levels incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed