BDBM50505837 CHEMBL4591327

SMILES CC(C)(O)Cn1c2ccccc2[nH]\c1=N/C(=O)c1cc(F)cc(c1)-c1cccnc1

InChI Key InChIKey=DJZWMTBYRCKZMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505837   

TargetEpidermal growth factor receptor(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50505837(CHEMBL4591327)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of GST-fusion tagged EGFR L858R/T790M/C797S triple mutant (unknown origin) (696 to 1022 residues) expressed in insect cells assessed as de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50505837(CHEMBL4591327)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant GST-tagged wild type EGFR expressed in baculovirus expression system assessed as decrease in phosphorylation of ULigh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed