BDBM50505361 CHEMBL4530348

SMILES CC(C)(C)c1ccc(cc1)C(=O)NCCN1C(=O)c2cccc3c(Sc4ccc(Br)cc4)ccc(C1=O)c23

InChI Key InChIKey=FDTLPRMIVMUNSD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50505361   

TargetApoptosis regulator Bcl-2(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50505361(CHEMBL4530348)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of Bcl-2 (unknown origin) by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50505361(CHEMBL4530348)
Affinity DataIC50: 4.45E+3nMAssay Description:Inhibition of biotinylated Bim peptide (81 to 106 residues) binding to His-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) cells preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50505361(CHEMBL4530348)
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of biotinylated Bim peptide (81 to 106 residues) binding to His-tagged human Bcl-2 expressed in Escherichia coli BL21 (DE3) cells preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed