BDBM50504715 CHEMBL4514446

SMILES CC(Cn1cnc2ccccc12)(C(O)=O)P(O)(O)=O

InChI Key InChIKey=QUDUQQDLBUPHAQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50504715   

TargetGeranylgeranyl transferase type-2 subunit alpha/beta(Rat)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50504715(CHEMBL4514446)
Affinity DataIC50: 8.10E+5nMAssay Description:Inhibition of recombinant rat RabGGTase expressed in Escherichia coli using Rab7 as substrate and [3H]geranylgeranyl pyrophosphate after 20 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50504715(CHEMBL4514446)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using [14C] IPP and FPP as substrate preincubated for 10 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50504715(CHEMBL4514446)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant rat FTase expressed in Escherichia coli using dansyl-GCVLS as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50504715(CHEMBL4514446)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FDPS (unknown origin) using [14C] IPP and GPP as substrate preincubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Rat)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50504715(CHEMBL4514446)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant rat GGtase-1 expressed in Escherichia coli using dansyl-GCVLL as substrate after 1.5 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed