BDBM50504254 CHEMBL4569755

SMILES Clc1ccc(\C=N\c2nnc(o2)-c2cccnc2)cc1

InChI Key InChIKey=BPLKICTZHXZIOZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50504254   

TargetEpidermal growth factor receptor(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50504254(CHEMBL4569755)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR catalytic domain (668 to 1210 residues) expressed in baculovirus expression system using TK-biotin pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50504254(CHEMBL4569755)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant COX-2 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50504254(CHEMBL4569755)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of ovine COX-1 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed