BDBM50503899 CHEMBL4471668

SMILES CCCCc1nc(Cl)c(CNC(=O)C(CS)Cc2ccc3ccccc3c2)n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=CHKOUVAKPRIMRS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503899   

TargetNeprilysin(Human)
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Curated by ChEMBL
LigandPNGBDBM50503899(CHEMBL4471668)
Affinity DataIC50: 398nMAssay Description:Inhibition of NEP (unknown origin) preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50503899(CHEMBL4471668)
Affinity DataKi:  158nMAssay Description:Displacement of Europium-labeled angiotensin-2 from human AT1 receptor expressed in CHOK1 cell membranes after 120 mins by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed