BDBM50503890 CHEMBL4515703

SMILES CCCCC(CS)C(=O)NCc1c(Cl)nc(CCCC)n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=MAMIBVRNOYOUBU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503890   

TargetNeprilysin(Human)
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50503890(CHEMBL4515703)
Affinity DataIC50: 631nMAssay Description:Inhibition of NEP (unknown origin) preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50503890(CHEMBL4515703)
Affinity DataKi:  126nMAssay Description:Displacement of Europium-labeled angiotensin-2 from human AT1 receptor expressed in CHOK1 cell membranes after 120 mins by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed