BDBM50503709 CHEMBL4588123

SMILES OCCn1nc(nc1[C@@H]1CCCCN1Cc1ccccc1)C1CCOCC1

InChI Key InChIKey=YZBNVGLIRLAAIK-UHFFFAOYSA-N

Data  4 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50503709   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataKd:  890nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK1 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK2 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataKd:  7.90E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK4 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK3 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataEC50:  420nMAssay Description:Inhibition of PDK1 (unknown origin) using PDH E1 as substrate measured after 30 mins by kinase-glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed