BDBM50503708 CHEMBL4457385

SMILES CCCCN(Cc1ccncc1)C(=O)c1cc(n[nH]1)-c1ccccc1O

InChI Key InChIKey=AGRXCVAQHVIZKP-UHFFFAOYSA-N

Data  4 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50503708   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataKd:  1.07E+4nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK4 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK2 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataEC50:  1.99E+3nMAssay Description:Inhibition of PDK1 (unknown origin) using PDH E1 as substrate measured after 30 mins by kinase-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataKd:  5.80E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK1 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataKd:  7.80E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK3 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed